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Foundations and chip architecture

Welcome to Gene Chip Technology

From DNA hybridisation to a measurable signal

Chip components, probes and array design

Major types of gene chip

Checkpoint: gene chip fundamentals

Laboratory workflow and data interpretation

From biological sample to labelled target

Hybridisation, washing and scanning

Quality control and experimental design

Understanding gene expression profiles

Checkpoint: laboratory workflow

Bioinformatics, applications and the future

Preprocessing, normalisation and statistical analysis

Heat maps, clustering and pathway interpretation

Biomedical, agricultural and research applications

Limitations, ethics and comparison with sequencing

Case study: selecting and interpreting a gene chip

Final assessment: applying gene chip knowledge

A practical, mixed-level introduction to DNA microarrays and gene chip technology, covering molecular principles, laboratory workflows, data analysis, biomedical applications, limitations and comparison with sequencing.

A practical introduction to DNA microarrays, gene-expression profiling, genotyping, data analysis and biomedical applications. Designed for mixed-level learners, with technical concepts explained from first principles.

Gene Chip Technology: Principles, Applications and Future Perspectives

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