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How DNA is copied

Why replication must be accurate

The replication fork and its enzymes

Leading and lagging strand synthesis

Knowledge check: replication

Proofreading, repair and chromosome ends

Proofreading and replication fidelity

DNA damage and repair pathways

Telomeres and the end-replication problem

Knowledge check: DNA maintenance

Mutation and genome variation

Types and causes of mutation

From DNA change to biological effect

Genetic stability and evolution

Final knowledge check: genome stability

Understand how cells copy their genomes, correct DNA damage and preserve genetic information while allowing variation.

Explore the molecular machinery that copies DNA, detects damage and protects genome integrity across cell generations.

DNA Replication, Repair and Genetic Stability

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