 <h1>Congratulations! 🎉 </h1>
    <p style="color:#637381;">All done! You’ve completed another milestone.</p>

To continue, enter your details to log in.

We’ve sent a 6‑digit code to #MAIL_ADDRESS#\nPlease check your inbox or spam folder and enter the code below to continue.

Verification code sent

Thank you for the payment. You can now access {collectionName} by simply clicking the button below.

Yes, you’ve successfully ordered! 🎉

Unlock This Exclusive Course

It seems that your email address is not currently on the authorized access list. Please ensure you are using the email address that was invited, or contact the content owner for assistance.

Verification Required for Access

Course Orientation and Required Information

Common and Not-So-Common Challenges in Genitourinary Pathology

Important Information Regarding CME

Disclosure of Relevant Financial Relationships

USCAP Luminaries in Pathology

WHO 5th Edition Renal Tumor Classification and Terminology Challenges

WHO Classification of Renal Tumours (5th Edition)

Changes in Terminology that Suggest Low Malignant Potential

Renal Oncocytic and Eosinophilic Tumors: Differential Diagnosis and IHC Strategy

Case 1

Differential Diagnosis and IHC Profiles

Immunohistochemistry in Renal Tumors with Cytoplasmic Eosinophilia (Oncocytic)

IHC Profile Table

Summary

Comparative Diagnostic Pitfalls: EVT and SDH-Deficient Renal Cell Carcinoma

Case 2

Comparative Features: EVT vs. SDH-Deficient RCC

Hereditary and Syndromic Renal Tumors: TSC, BHD, and Broader RCC Syndromes

Case 3

Renal Cell Carcinoma in Tuberous Sclerosis Complex (TSC)

Distribution by Histologic Subtypes

Tuberous Sclerosis–associated Renal Cell Carcinoma

Oncocytosis and Birt-Hogg-Dubé (BHD) Syndrome

Renal Tumors in Cases of Oncocytosis

Renal Parenchyma in Cases of Oncocytosis

BHD Syndrome Features

Hereditary Renal Cell Carcinoma Syndromes

Applied Case-Based IHC Selection and Consequences of Misclassification

Case 4

IHC Findings

Follow-up Cases (Observations)

Lessons Learned

Penalty for Misdiagnosis

Recommended Antibody Panel

Bladder and Urothelial Benign Mimics of Carcinoma

Case 5

Pseudocarcinomatous Urothelial Hyperplasia

Case 6

Pathologic Findings

Cystitis Cystica and Glandularis with Intestinal Metaplasia

Knowledge Checks and Course Feedback

Quiz 1: WHO 5th Edition Updates and Low Malignant Potential Terminology

Quiz 2: Oncocytic Renal Tumors and IHC Profiles

Quiz 3: EVT Versus SDH-Deficient Renal Cell Carcinoma

Quiz 4: TSC and BHD-Associated Renal Tumors

Quiz 5: Urothelial Benign Mimics and Malignant Look-Alikes

Survey 1: Course Experience and Relevance to Practice

Survey 2: Self-Assessment of Learning Outcomes

Stay current with the latest WHO 5th Edition updates while sharpening your diagnostic instincts for challenging genitourinary (GU) cases. Diagnostic Challenges and WHO Updates in Genitourinary Pathology is a case-driven, CME-ready course designed for practicing surgical pathologists, fellows, and residents who interpret renal and urothelial specimens. Through expertly curated cases, you will navigate oncocytic and eosinophilic renal tumors, hereditary and syndromic entities (including TSC and BHD), and benign mimics that resemble carcinoma in the bladder. You will learn how to select high-yield IHC panels, avoid common pitfalls (such as EVT versus SDH-deficient RCC), and apply updated terminology that reflects low malignant potential—improving communication with clinicians and patient management. The program blends practical pearls with evidence-based updates, reinforcing learning with targeted quizzes and structured knowledge checks. By the end, you will be able to confidently integrate WHO 5th Edition classifications into day-to-day sign-out, recognize when genetic syndromes should be considered, and understand the real-world impact of misclassification on treatment and follow-up. If you’re seeking a focused, practice-enhancing update that elevates accuracy and efficiency at the microscope, this course is for you.

Diagnostic Challenges and WHO Updates in Genitourinary Pathology

<div class="simple-box-wrapper">
    <div class="simple-box">
        <div class="column">
            <p>The field of genitourinary pathology is currently undergoing a significant transformation, driven largely by the refinements introduced in the WHO 5th Edition Classification of Renal Tumours. This course provides a comprehensive examination of these updates, focusing on the critical shifts in terminology—particularly those identifying tumors of low malignant potential—and the diagnostic nuances required for contemporary practice. By integrating the latest evidence-based criteria, pathologists can better navigate the complexities of renal neoplasia, ensuring that diagnostic reports align with the most current international standards and prognostic frameworks.</p>

<p>Central to this educational initiative is a case-based exploration of diagnostic pitfalls, with a specific emphasis on the differential diagnosis of oncocytic and eosinophilic renal tumors. Participants will evaluate the immunohistochemical strategies necessary to distinguish between entities such as Eosinophilic Vacuolated Tumor (EVT) and SDH-deficient renal cell carcinoma, as well as the recognition of syndromic presentations including Tuberous Sclerosis Complex (TSC) and Birt-Hogg-Dubé (BHD) syndrome. Furthermore, the curriculum addresses common mimics in bladder and urothelial pathology, highlighting the clinical consequences of misclassification and providing a robust framework for the application of targeted antibody panels in daily diagnostic workflows.</p>
        </div>
    </div>
</div>
